Heightened levels of violence, worsening security, and ongoing access constraints continue to hamper efforts to reach those most in need. Despite massive operational challenges, UNICEF Syria and partners sustained the scale of humanitarian operations, improving the quality of the response while expanding access. A total of 2.4 million children were vaccinated against polio and three multi-antigen campaigns screened more than 1.7 million children under-five (including more than 633,000 in hard-to-reach areas) and vaccinated some 444,000 children who had defaulted. As part of our mission to give the most vulnerable among us the foundation for a better future, we used proceeds from the PxP Festival to help UNICEF procure 270,300 doses of the polio vaccine, reaching approximately 30,000 Syrian refugee children.